
First Author Publications


A large-scale analysis of alternative splicing reveals a key role of QKI in lung cancer.
de Miguel FJ, Pajares MJ, Martínez-Terroba E, et al.
Mol Oncol. 2016 Aug 3;1-13.
PubMed | Molecular Oncology

Identification of alternative splicing events regulated by the oncogenic factor SRSF1 in lung cancer.
de Miguel FJ, Sharma RD, Pajares MJ, et al.
Cancer Res. 2014 Feb 15;74(4):1105-15
PubMed | Cancer Research
Co-authored Publications
Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein.
Tripathi BK, Anderman MF, Bhargava D, Boccuzzi L, Qian X, Wang D, Durkin ME, Papageorge AG, de Miguel FJ, Politi K, Walters KJ, Doroshow JH, Lowy DR.
Nat Commun. 2021 Dec 3;12(1):6941.
PubMed | Nature Communications
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB.
Cell. 2021 Jan 7;184(1):76-91.e13.
PubMed | Cell
Antiangiogenic Vascular Endothelial Growth Factor-Blocking Peptides Displayed on the Capsid of an Infectious Oncolytic Parvovirus: Assembly and Immune Interactions.
Grueso E, Sánchez-Martínez C, Calvo-López T, de Miguel FJ, Blanco-Menéndez N, Fernandez-Estevez M, Elizalde M, Sanchez J, Kourani O, Martin D, Tato A, Guerra M, Andrés G, Almendral JM.
J Virol. 2019 Sep 12;93(19):e00798-19.
PubMed | Journal of Virology
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors.
Ayeni D, Miller B, Kuhlmann A, Ho PC, Robles-Oteiza C, Gaefele M, Levy S, de Miguel FJ, Perry C, Guan T, Krystal G, Lockwood W, Zelterman D, Homer R, Liu Z, Kaech S, Politi K.
J Immunother Cancer. 2019 Jul 10;7(1):172.
PubMed | Journal for Immunotherapy of Cancer
Comparison of RNA-seq and microarray platforms for splice event detection using a cross-platform algorithm.
Romero JP, Ortiz-Estévez M, Muniategui A, Carrancio S, de Miguel FJ, Carazo F, Montuenga LM, Loos R, Pío R, Trotter MWB, Rubio A.
BMC Genomics. 2018 Sep 25;19(1):703.
PubMed | BMC Genomics
A novel protein-based prognostic signature improves risk stratification to guide clinical management in early-stage lung adenocarcinoma patients.
Martínez-Terroba E, Behrens C, de Miguel FJ, Agorreta J, Monsó E, Millares L, Sainz C, Mesa-Guzman M, Pérez-Gracia JL, Lozano MD, Zulueta JJ, Pio R, Wistuba II, Montuenga LM, Pajares MJ.
J Pathol. 2018 Aug;245(4):421-432.
PubMed | The Journal of Pathology
Blockade of the Complement C5a/C5aR1 Axis Impairs Lung Cancer Bone Metastasis by CXCL16-mediated Effects.
Ajona D, Zandueta C, Corrales L, Moreno H, Pajares MJ, Ortiz-Espinosa S, Martínez-Terroba E, Perurena N, de Miguel FJ, Jantus-Lewintre E, Camps C, Vicent S, Agorreta J, Montuenga LM, Pio R, Lecanda F.
Am J Respir Crit Care Med. 2018 May 1;197(9):1164-1176.
PubMed | AAJCCM
EventPointer: an effective identification of alternative splicing events using junction arrays.
Romero JP, Muniategui A, De Miguel FJ, Aramburu A, Montuenga L, Pio R, Rubio A.
BMC Genomics. 2016 Jun 17;17:467.
PubMed | BMC Genomics